Table 2: Distribution of TGFB1 and VEGFA polymorphism genotypes in the analyzed patient cohort ().

Gene/polymorphismHomozygous majorHeterozygousHomozygous minorHWE valueMAFMAF EU population [51]

A/AA/GG/G
TGFB1 (rs1800470)224 (33.8%)310 (46.8%)129 (19.5%)0.2742.838
A/AA/CC/C
VEGFA (rs699947)186 (27.6%)322 (47.7%)167 (24.7%)0.2548.650

Genotypes of TGFB1 and VEGFA were successfully established for 663 (98.1%) and 675 (99.9%) patients, respectively. MAF: minor allele frequency; EU: European Union; HWE: Hardy-Weinberg equilibrium.