Disease Markers / 2017 / Article / Tab 3

Research Article

Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma

Table 3

Cox proportional hazard regression analysis of patients’ overall survival.

VariablesUnivariableMultivariable
Hazard ratio95% CI valueHazard ratio95% CI value

Gender (female versus male)0.7850.493–1.3320.407
Age (<50 versus ≥50)0.5510.316–0.8300.0040.6080.331–1.1110.106
AFP (≥400 ng/mL versus <400 ng/mL)1.6081.124–2.3000.0091.6571.149–2.3870.007
ALT (>80 IU/L versus ≤80 IU/L)1.4731.016–2.1350.0411.2990.952–2.1130.541
Albumin (>35 g/L versus ≤35 g/L)0.3270.540–1.2280.327
Bilirubin (>20 μmol/L versus ≤20 μmol/L)1.3800.747–2.5510.304
Number of tumor lesions (single versus multiple)0.4380.296–0.6480.0000.4820.297–0.7830.003*
Vascular invasion (absent versus present)0.4680.307–0.7120.0060.4760.277–0.8190.007*
Cirrhosis (absent versus present)0.5530.385–0.7920.0010.5430.370–0.7970.002*
Histological differentiation
Moderately versus well1.1460.674–1.9480.614
Poorly versus well1.5930.840–3.0200.153
Greatest tumor diameter
(≥5 cm versus <5 cm)1.6191.012–2.5910.0441.4220.976–2.0740.067
EpCAM (positive versus negative)2.0531.272–3.3130.0032.0301.252–3.2900.004
CD13 (positive versus negative)1.6251.022–2.5020.0401.4690.908–2.3780.117

CI: confidence interval; AFP: alpha-fetoprotein; ALT: alanine aminotransferase; indicates .