Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma

Table 3

Sensitivity and specificity of miR-132-3p and number of true positive, true negative, false positive, and false negative tests, calculated for maximum Youden’s Index (YI) and fixed false positive rates (FPRs) of 0%, 5%, and 10%.

FPR (%)	Cut-off	Sensitivity (%)	Specificity (%)	True positive ()	True negative ()	False positive ()	False negative ()
	Maximum YI							0.100	86	61	19	27	17	3
0	0.014	5	100	1	44	0	21
5	0.047	23	95	5	42	2	17
10	0.063	36	90	8	39	5	14