Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma

Table 6

Sensitivity and specificity of the and algorithm for miR-132-3p/miR-126 and number of true positive, true negative, false positive, and false negative tests, calculated for maximum Youden’s Index (YI) and fixed false positive rates (FPRs) of 0%, 5%, and 11%.

FPR (%)	Cut-off		Sensitivity (%)	Specificity (%)	True positive ()	True negative ()	False positive ()	False negative ()
	Maximum YI	0.102							34.27	77	86	17	38	6	5
0	0.132	0.62	9	100	2	44	0	20
5	0.085	19.51	41	95	9	42	2	13
11	0.095	62.60	64	89	14	39	5	8