Research Article

Associations between the Epithelial-Mesenchymal Transition Phenotypes of Circulating Tumor Cells and the Clinicopathological Features of Patients with Colorectal Cancer

Figure 1

Detection of CTCs and CTMs in the peripheral blood of patients with colorectal cancer. (a) EpCAM expression (red fluorescence) in epithelial CTCs (E-CTCs). (b) EpCAM and vimentin expression (red and green fluorescence, resp.) in epithelial/mesenchymal CTCs (E/M-CTCs). (c) Vimentin expression (green fluorescence) in mesenchymal CTCs (M-CTCs). (d) CTMs, consisting of E/M-CTCs. Magnification, ×100. CTC, circulating tumor cell; CTMs, circulating tumor microemboli; EpCAM, epithelial cell adhesion molecule.
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