Risk Factors for the Development of Refeeding Syndrome-Like Hypophosphatemia in Very Low Birth Weight Infants
Table 2
Parameters of parenteral administration of nutrition and minerals during the first week of life in very low birth weight infants stratified according to serum phosphate levels.
Parameter
All ()
Hypophosphatemia ()
Normophosphatemia ()
value
Parenteral administration on the first day of life
Glucose infusion rate, mg/kg/min
4.2 (3.9–4.9)
5.0 (4.2–5.3)
4.1 (3.8–4.4)
0.005
Calcium, mg/kg/day
53.4 (47.9–60.4)
53.4 (50.2–59.7)
53.4 (36.9–60.4)
0.543
Initial day of parenteral administration
Amino acids, days
2.0 (1.0–3.0)
2.0 (1.3–2.8)
2.0 (1.3–3.0)
0.933
Phosphate, days
4.0 (3.0–5.0)
4.0 (3.3–5.8)
4.0 (3.0–5.0)
0.268
Potassium, days
3.0 (2.3–4.8)
3.0 (3.0–3.8)
3.0 (2.0–5.0)
0.712
Final day of parenteral administration
Calcium, days
3.0 (3.0–4.0)
3.0 (3.0–4.0)
4.0 (3.0–4.0)
0.628
Daily nutritional intake during the first week
Amino acids, g/kg/day
1.3 (1.0–1.5)
1.4 (0.9–1.7)
1.3 (1.0–1.5)
0.404
Calcium, mg/kg/day
49.5 (40.8–55.0)
49.5 (43.2–6.8)
49.5 (36.9–55.0)
0.965
Phosphate, mg/kg/day
22.2 (16.4–29.2)
22.2 (16.0–32.5)
21.7 (16.5–28.6)
0.704
Values are expressed as median (interquartile range). Significant differences between the groups () are indicated in bold font.
