Serum Uric Acid as an Independent Risk Factor for the Presence and Severity of Early-Onset Coronary Artery Disease: A Case-Control Study
Table 4
Association of serum uric acid categories and Gensini score in male and female EOCAD patients.
Variable
Male EOCAD patients
Female EOCAD patients
Normouricemia (<7.0 mg/dl)
Hyperuricemia (≥7.0 mg/dl)
value
Normouricemia (<6.0 mg/dl)
Hyperuricemia (≥6.0 mg/dl)
value
Number,
764
222
—
82
24
—
Age, years
43.74 ± 4.55
43.40 ± 1.99
0.333
46.18 ± 3.59
45.18 ± 3.06
0.379
BMI
26.59 ± 3.54
27.86 ± 3.65
<0.001
25.94 ± 3.52
25.98 ± 4.07
0.967
FBG, mmol/l
6.07 ± 2.53
5.72 ± 2.06
0.067
6.59 ± 3.29
8.04 ± 5.11
0.197
TG, mmol/l
2.01 ± 1.53
2.78 ± 2.49
<0.000
1.83 ± 2.10
1.63 ± 0.50
0.744
TC, mmol/l
4.52 ± 1.27
4.65 ± 1.38
0.170
4.45 ± 1.17
4.40 ± 2.36
0.953
HDL-C, mmol/l
1.07 ± 0.26
1.03 ± 0.25
0.057
1.21 ± 0.29
1.04 ± 0.23
0.042
LDL-C, mmol/l
2.64 ± 0.97
2.59 ± 1.02
0.586
2.45 ± 0.86
2.69 ± 1.93
0.686
Lp(a), mmol/l
289.96 ± 344.69
262.95 ± 281.29
0.286
331.47 ± 345.69
257.07 ± 193.18
0.486
SCr, μmol/l
85.71 ± 14.80
92.55 ± 15.89
<0.001
69.65 ± 14.31
77.48 ± 13.46
0.017
Gensini score
48.25 ± 37.23
56.33 ± 45.80
0.017
26.22 ± 22.50
71.77 ± 64.33
0.044
EOCAD: early-onset coronary artery disease; BMI: body mass index; FBG: fasting blood glucose; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp (a): lipoprotein (a); SCr: serum creatinine; UA: uric acid. Continuous variables are expressed as mean ± SD. The value of the continuous variables was calculated by unpaired t-test.
