Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia
Table 1
Comparison of clinical data within the study population.
(a)
Clinical data
Maternal preeclamptic group ()
Maternal control group ()
value
Age of women (years)
30.7 ± 6.2
32.0 ± 4.3
0.129
BMI (kg/m2)
26 ± 3.1
25 ± 4.3
<0.05
WBC (103/μl)
10.6 ± 2.3
10.7 ± 2.3
0.712
RBC (106/μl)
4.1 ± 0.5
4.1 ± 0.4
0.648
HB (g/dl)
12.2 ± 1.4
12.4 ± 1.1
0.474
HCT (%)
35.7 ± 3.4
36.2 ± 2.5
0.313
MCV (fl)
85.4 ± 6.5
87.1 ± 5.2
0.071
MCHC (g/dl)
34.3 ± 2.6
33.8 ± 1.7
0.126
PLT (103/μl)
203.4 ± 60.5
220.4 ± 54.2
0.057
History of miscarriage n (%)
16 (19%)
13 (15%)
0.564
Week of delivery for early PE ()
31.6 ± 2.0
38.5 ± 1.0
<0.0001
Week of delivery for late PE (N=55)
37.6 ± 2.0
38.5 ± 1.0
<0.01
(b)
Clinical data
Fetal preeclamptic group ()
Fetal control group ()
value
Baby weight (g)
2469 ± 923
3407 ± 448
<0.001
Baby height (cm)
49.0 ± 6.4
54.1 ± 2.8
<0.001
Apgar score—1 minute
8.6 ± 1.4
9.4 ± 0.8
<0.001
Baby sex (son), N (%)
52 (60%)
38 (45%)
<0.05
The values are presented as mean ± standard deviation. For data analysis, Student’s t-test was used. For data analysis, the chi-squared test was used; BMI: body mass index; WBC: white blood cells; RBC: red blood cells; HB: haemoglobin concentration; HCT: haematocrit; MCV: mean corpuscular volume; MCHC: mean corpuscular haemoglobin concentration; PLT: platelets; kg/m2: kilograms/meter square; μl: microlitre; g/dl: grams/decilitre; %: percent; fl: femtolitre; g: grams; cm: centimetre; N: number of cases.
