Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia

Table 2

Linkage disequilibrium between studied polymorphisms.

	MMP3 rs35068180 (D’)	MMP9 rs3918242 (D’)	MMP2 rs2285053 (D’)	MMP2 rs243865 (D’)
MMP1 rs1799750 (D’)	0.22	0.17	0.03	0.03
MMP3 rs35068180 (D’)		0.30	0.27	0.07
MMP9 rs3918242 (D’)			0.31	0.07
MMP2 rs2285053 (D’)				0.25

D’is equal to D scaled in [−1,1] range where D is the deviation between the expected haplotype frequency and the observed frequency.