Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

Figure 1

Histopathology of placenta accreta syndrome. (a) High-power picture of decidualised endometrium as a result of pregnancy. Stromal cells are large, pale, and polygonal. (b) Low-power image of decidualised endometrium on the surface with underlying congested myometrial blood vessels and myometrium. (c) Low-power image of PAS showing chorionic villi in direct contact with myometrium (no intervening decidua). (d) Chorionic villus with polar trophoblast invading myometrial muscle. (e) Nonadherent area of the same placenta where decidua is seen between villi (bottom right) and myometrium (top left). (f) PAS—chorionic villi in direct contact with muscle; a multinucleated extravillous trophoblast is seen in the top right.

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