The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus
Table 1
Baseline characteristics of the patients.
Characteristic
Control ()
CHD ()
CHD-T2DM ()
Age (years)
61.9 ± 14.8
61.8 ± 11.1
64.4 ± 10.9
Male (%)
48 (36.4%)
109 (44.9%)
76 (43.4%)
Hypertension (%)
37 (28.0%)
129 (53.1%)
118 (67.4%)#
Current smoking (%)
3 (2.3%)
20 (8.2%)
19 (10.9%)#
Alcohol intake (%)
42 (31.8%)
67 (27.6%)
59 (33.7%)
HDL (mmol/L)
1.30 ± 0.03
1.29 ± 0.02
1.18 ± 0.02
LDL (mmol/L)
2.82 ± 0.06
2.88 ± 0.05
2.79 ± 0.06
Total cholesterol (mmol/L)
4.73 ± 0.09
4.79 ± 0.07
4.60 ± 0.10
Triglyceride (mmol/L)
1.72 ± 0.09
1.79 ± 0.07
2.23 ± 0.12
Lipoprotein (a) (g/L)
1.28 ± 0.02
1.26 ± 0.02
1.21 ± 0.02
Lipoprotein (b) (g/L)
0.98 ± 0.03
1.02 ± 0.02
1.04 ± 0.03
Blood glucose (mmol/L)
5.32 ± 0.15
5.33 ± 0.09
8.65 ± 0.29#
hs-TnI (ng/mL)
0.012 ± 0.003
0.253 ± 0.104
0.251 ± 0.006
CKMB (ng/mL)
1.01 ± 0.07
2.35 ± 0.64
2.97 ± 0.61
Data are presented as mean ± standard deviation or proportions. HDL: high-density lipoprotein; LDL: low-density lipoprotein; hs-TnI: high-sensitive troponin I; CKMB: creatine kinase MB. versus control; versus CHD.