Research Article

The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus

Table 1

Baseline characteristics of the patients.

CharacteristicControl ()CHD ()CHD-T2DM ()

Age (years)61.9 ± 14.861.8 ± 11.164.4 ± 10.9
Male (%)48 (36.4%)109 (44.9%)76 (43.4%)
Hypertension (%)37 (28.0%)129 (53.1%)118 (67.4%)#
Current smoking (%)3 (2.3%)20 (8.2%)19 (10.9%)#
Alcohol intake (%)42 (31.8%)67 (27.6%)59 (33.7%)
HDL (mmol/L)1.30 ± 0.031.29 ± 0.021.18 ± 0.02
LDL (mmol/L)2.82 ± 0.062.88 ± 0.052.79 ± 0.06
Total cholesterol (mmol/L)4.73 ± 0.094.79 ± 0.074.60 ± 0.10
Triglyceride (mmol/L)1.72 ± 0.091.79 ± 0.072.23 ± 0.12
Lipoprotein (a) (g/L)1.28 ± 0.021.26 ± 0.021.21 ± 0.02
Lipoprotein (b) (g/L)0.98 ± 0.031.02 ± 0.021.04 ± 0.03
Blood glucose (mmol/L)5.32 ± 0.155.33 ± 0.098.65 ± 0.29#
hs-TnI (ng/mL)0.012 ± 0.0030.253 ± 0.1040.251 ± 0.006
CKMB (ng/mL)1.01 ± 0.072.35 ± 0.642.97 ± 0.61

Data are presented as mean ± standard deviation or proportions. HDL: high-density lipoprotein; LDL: low-density lipoprotein; hs-TnI: high-sensitive troponin I; CKMB: creatine kinase MB. versus control; versus CHD.