The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus

Table 2

Univariate regression analysis for the association of TMAO with demographic characteristics between CHD or CHD-T2DM patients and control participants.

Characteristic	CHD		CHD-T2DM
	OR (95% CI)	value	OR (95% CI)	value
Age	1.066 (1.046–1.088)	0.110	1.083 (0.963–1.203)	0.124
Male	1.413 (0.911–2.190)	0.122	1.383 (1.160–1.606)	0.145
HDL	0.885 (0.436–1.795)	0.735	0.276 (0.119–0.635)	0.003
LDL	1.126 (0.827–1.534)	0.450	0.958 (0.705–1.302)	0.783
Total cholesterol	1.060 (0.867–1.295)	0.569	0.915 (0.747–1.120)	0.388
Triglyceride	1.073 (0.859–1.340)	0.534	1.366 (1.088–1.716)	0.007
Lipoprotein (a)	0.670 (0.263–1.709)	0.402	0.253 (0.084–0.764)	0.015
Lipoprotein (b)	1.438 (0.706–2.927)	0.317	1.456 (0.768–2.759)	0.249
Blood glucose	1.001 (0.865–1.158)	0.993	2.388 (1.874–3.043)	0.001
hs-TnI	1.737 (0.283–10.06)	0.371	1.724 (0.001–8.053)	0.013
CKMB	1.446 (1.044–2.002)	0.026	1.867 (1.305–2.672)	0.001
TMAO	3.621 (2.581–5.080)	0.001	9.581 (5.451–16.840)	0.001