Positive Association between EDN1 rs5370 (Lys198Asn) Polymorphism and Large Artery Stroke in a Ukrainian Population

Table 2

General characteristics of the study population.

Parameter	Cases; ()	Controls; ()	P
Age, years	66.7 ± 10.1	68.1 ± 13.9	0.261
Sex, female/male	89/111	75/125	0.155
Body mass index, kg/m^2	27.9 ± 3.7	27.3 ± 4.6	0.105
Systolic BPs, mmHg	167.9 ± 28.7	151.7 ± 22.6	<0.001
Diastolic BP, mmHg	96.0 ± 15.5	86.5 ± 11.7	<0.001
Pulse BP, mmHg	71.9 ± 22.4	65.2 ± 17.2	0.002
Mean BPs, mmHg	119.9 ± 17.9	108.3 ± 14.0	<0.001
Fasting glucose, mmol/L	6.05 ± 1.5	5.25 ± 0.7	<0.001
Total cholesterol, mmol/L	4.98 ± 1.46	4.75 ± 1.52	0.124
HDL cholesterol, mmol/L	1.01 ± 0.29	1.09 ± 0.38	0.018
LDL cholesterol, mmol/L	3.16 ± 1.39	2.94 ± 1.17	0.087
Triglyceride, mmol/L	1.67 ± 0.78	1.54 ± 0.66	0.073
Current smokers, n (%)	60 (30.0)	55 (27.5)	0.581
T2DM, n (%)	50 (25.0)	19 (9.5)	<0.001
Arterial hypertension, n (%)	150 (75.0)	116 (58.0)	<0.001

Categorical variables were compared by χ² test, continuous variables by t-test.