Adipose Tissue-Derived Biomarkers of Intestinal Barrier Functions for the Characterization of Diarrhoea-Predominant IBS
Table 1
Comparison of GSRS score between HC and D-IBS and between D-IBS (−) and D-IBS (+) patients.
HC
D-IBS
D-IBS (−)
D-IBS (+)
GSRS single items
Epigastric pain
1 (1–1)
3.5 (1–7)
5 (1–7)
2 (1–6)
Gastric hunger pain
1 (1–1)
2 (1–7)
1 (1–7)
2 (1–5)
Abdominal continuous pain
1 (1–1)
1 (1–5)
3 (1–5)
1 (1–5)
Abdominal colic pain
1 (1–1)
2 (1–7)
5 (1–7)
1 (1–7)
Abdominal indefinite pain
1 (1–1)
1 (1–5)
1 (1–5)
1 (1–3)
Nausea
1 (1–1)
1 (1–6)
2 (1–6)
1 (1–4)
Burping
1 (1–1)
2 (1–7)
1 (1–7)
3 (1–5)
Borborygmi
1 (1–1)
2 (1–7)
2 (1–7)
2 (1–7)
Abdominal distension
1 (1–1)
5 (1–7)
5 (1–7)
5 (1–7)
Flatulence
1 (1–1)
4.5 (1–7)
5 (1–7)
3 (1–6)
Postprandial fullness
1 (1–1)
3 (1–7)
4 (1–7)
3 (1–5)
Early satiety
1 (1–1)
1 (1–7)
1 (1–7)
1 (1–7)
Increased passage of stools
1 (1–1)
1 (1–7)
1 (1–3)
1 (1–7)
Soft stool
1 (1–1)
1 (1–7)
3 (1–5)
1 (1–7)
Urgent bowel movement
1 (1–1)
1.5 (1–7)
1 (1–7)
2 (1–7)
Bristol score
4 (3–4)
4 (3–7)
5 (3–6)
3 (3–7)
GSRS cluster scores
Pain syndrome
6 (6–6)
13 (6–25)
16 (7–25)
11 (6–22)
Indigestion syndrome
6 (6–6)
19 (7–38)
19 (7–38)
22 (12–36)
Diarrhoea syndrome
3 (3–3)
5 (3–21)
7 (3–15)
5 (3–21)
HC: healthy controls; D-IBS (+)/(−): diarrhoea-predominant IBS according to presence/absence of impaired permeability. Data are expressed as median and range and were analysed by rank sum test. ().
