Research Article
Gamma-Glutamyltransferase and Risk of Acute Coronary Syndrome in Young Chinese Patients: A Case-Control Study
Table 1
Demographic and clinical characteristics of patients.
| | Control group () | ACS group () |
| | Age (years) | 50.2 ± 10.6 | 48.6 ± 8.5 | | CAD family history [n (%)] | 18 (7.9%) | 15 (6.9%) | | Current smokers [n (%)] | 35 (15.4%) | 85 (39.4%)# | | Past smokers [n (%)] | 8 (3.5%) | 10 (4.6%) | | Pack years of smoking | 6.8 ± 4.5 | 15.3 ± 8.2# | | Men [n (%)] | 110 (50.7%) | 168 (77.8%)# | | Hypertension [n (%)] | 38 (16.7%) | 45 (20.8%) | | Systolic blood pressure (mmHg) | 123.0 ± 13.9 | 121.5 ± 12.8 | | Diastolic blood pressure(mmHg) | 73.4 ± 8.7 | 74.5 ± 8.5 | | Diabetes mellitus [n (%)] | 20 (8.4%) | 24 (11.1%) | | Fasting blood glucose (mg/dL) | 92.3 ± 15.8 | 95.4 ± 16.2 | | Dyslipidemia [n (%)] | 58 (25.6%) | 72 (33.3%) | | Triglyceride (mg/dL) | 150.8 ± 28.0 | 179.1 ± 28.4# | | Total cholesterol (mg/dL) | 184.2 ± 39.6 | 188.4 ± 38.4 | | Low-density lipoprotein cholesterol (mg/dL) | 126.2 ± 26.3 | 130.6 ± 28.5 | | High-density lipoprotein cholesterol (mg/dL) | 43.3 ± 13.8 | 41.2 ± 13.4 | | Overweight/obesity [n (%)] | 63 (27.9%) | 72 (33.3%) | | Body mass index (kg/m2) | 23.2 ± 5.6 | 24.5 ± 6.1 | | eGFR (ml/min/1.73 m2) | 115.1 ± 39.7 | 111.0 ± 35.8 | | hs-CRP (mg/dL) | 2.21 (0.75–7.65) | 5.54 (1.14–10.31) | | GGT (U/L) | 21.5 (14.3–55.3) | 36.7 (16.8–78.6)# | | AST (U/L) | 29 (18–47) | 135 (37–265)# | | ALT (U/L) | 26 (12–42) | 52 (18–124)# | | TBIL (μmmol/L) | 12.8 ± 6.8 | 13.7 ± 6.5 | | DBIL (μmmol/L) | 3.7 ± 2.5 | 4.0 ± 2.7 | | IBIL (μmmol/L) | 9.2 ± 5.0 | 9.7 ± 5.8 | | Ox-LDL(mg/dL) | 1.20 ± 0.83 | 3.24 ± 1.74# | | 10-year CVD event risk (%) | 5.1 ± 3.9 | 5.6 ± 3.5 |
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Categorical variables were presented as percentages; continuous variables were expressed as median (interquartile range) or mean ± standard deviation. ACS, acute coronary syndrome; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CVD, cardiovascular disease; DBIL, direct bilirubin; eGFR, estimated glomerular filtration rate; GGT, gamma-glutamyltransferase; hs-CRP, high-sensitivity C-reactive protein; IBIL, indirect bilirubin; ox-LDL, oxidized low-density lipoprotein; TBIL, total bilirubin; , . |
