Research Article

Association between a Single Nucleotide Polymorphism in the 3-UTR of ARHGEF18 and the Risk of Nonidiopathic Pulmonary Arterial Hypertension in Chinese Population

Table 2

Allele frequencies of rs3745357 in the ARHGEF18 gene among PAH patients and controls.

AllelePAH patientsPAH patientsaPAH patientsbControls value
Allele numbers (%)Allele numbers (%)Allele numbers (%)Allele numbers (%)Overall patients versus controlsPAHa versus controlsPAHb versus controls

Rs3745357C106 (45.3)60 (63.8)46 (32.9)157 (45.9)0.9320.0010.017
T128 (54.7)34 (36.2)94 (67.1)195 (54.1)

aPH patients without history of coronary heart disease; bPH patients with history of coronary heart disease.