Increased Cytokeratin 19 Fragment Levels Are Positively Correlated with Adenosine Deaminase Activity in Malignant Pleural Effusions from Adenocarcinomas

Table 1

Demographic characteristics, ADA levels, and CK19 of controls (benign pleural effusions) and malignant pleural effusions (cases) in 119 patients.

Demographic characteristics and pleural biomarkers	MPE ()	BPE ()	Test ( value)
Male, n (%)	15 (35.0)	36 (47.0)	Chi-squared = 0.608 ()
Female, n (%)	28 (65.0)	40 (53.0)	Chi-squared = 0.959 ()
Mean age (years ± SD)	62.33 ± 12.37	60.95 ± 21.37	()
Median total ADA levels (IU/L) in normal scale (IQR)	9.76 (6.74–13.90)	11.63 (6.64–34.32)	()
Median CK19 levels (ng/mL) in normal scale (IQR)	85.03 (24.61–362.3)	13.41 (7.06–32.30)	()

Abbreviations: MPE: malignant pleural effusion; BPE: benign pleural effusion; SD: standard deviation; ADA: adenosine deaminase; CK19: cytokeratin 19 fragments; IQR: interquartile range, 25th–75th percentiles.