Haplotypes of TNFα/β Genes Associated with Sex-Specific Paranoid Schizophrenic Risk in Tunisian Population

Table 5

TNFα haplotype frequencies of the rs909253, rs1799724, and rs361525 in control subjects, patients with schizophrenia, and according to paranoid subtype.

Haplotype	rs909253	rs1799724	rs361525	Controls % ()	Patients % ()	OR (95% CI)	value
1	A	C	G	48.1	30.4	1
2	A	C	A	16.7	21.4	2.07 (1.27–3.41)	0.003
3	G	C	G	14.4	17.8	2.03 (1.21–3.41)	0.007
4	G	C	A	11	14.1	1.98 (1.20–3.25)	0.007
5	A	T	G	5.2	5.5	1.87 (0.73–4.80)	0.19
6	A	T	A	2.4	5.5	3.45 (1.28–9.30)	0.015
7	G	T	G	1.5	2.5	1.73 (0.41–7.21)	0.45
8	G	T	A	0.7	2.8	7.99 (0.95–67.00)	0.056
Haplotype	rs909253	rs1799724	rs361525	Controls %	Paranoid%	OR (95% CI)	value
1	A	C	G	48.1	22.4	1
2	A	C	A	16.7	21.2	2.87 (1.35–6.12)	0.006
3	G	C	G	14.4	12	2.07 (0.85–5.06)	0.11
4	G	C	A	11	19.1	3.71 (1.91–7.21)	0.0001
5	A	T	G	5.2	9.7	6.20 (1.74–22.08)	0.005
6	A	T	A	2.4	6.7	6.14 (1.94–19.45)	0.002
7	G	T	G	1.5	4.5	3.23 (0.58–18.06)	0.18
8	G	T	A	0.7	4.1	22.75 (1.39–371.31)	0.029

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