Soluble HLA-I and HLA-II Molecules Are Potential Prognostic Markers of Progression of Systemic and Local Inflammation in Patients with COPD

Table 1

Characteristics of patients with COPD and healthy nonsmokers included in the study.

		COPD
	Healthy nonsmokers	Moderate	Severe
Subjects ()	21	52	53
Age (years)	51.3 ± 8.5	53.1 ± 5.7	57.1 ± 5.1
Smoking pack-years	0	35.4 ± 6.7	41.3 ± 5.8
FEV1% pred	103.2 ± 4.1	61.4 ± 5.1	39.4 ± 4.1
FEV1/FVC %	105.3 ± 3.5	62.1 ± 3.8	48.7 ± 8.1
Inspiratory capacity IC (%)	109.2 ± 2.3	67.6 ± 6.9	64.1 ± 7.1

Data were presented as mean ± SD. COPD: chronic obstructive pulmonary disease; pack-years: number of cigarette packs per day multiplied by the number of smoking years; FEV₁: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; IC: inspiratory capacity (%).