Circulating PGRN Levels Are Increased but Not Associated with Insulin Sensitivity or β-Cell Function in Chinese Obese Children

Table 3

Correlation of PGRN levels with clinical characteristics in obese groups.

Variable	r	value
BMI (kg·m^2)	0.742	0.001
Age (years)	−0.182	0.850
SBP (mmHg)	0.670	0.003
DBP (mmHg)	0.570	0.032
Insulin (μU/mL)	0.250	0.690
HbAC1 (%)	0.219	0.832
Glucose (mmol/L)	0.080	0.968
HOMA-IR	0.260	0.668
HOMA-β	−0.222	0.750
Insulinogenic index, ΔI30/ΔG30 (μU/mL per mmol/L)	0.261	0.692
C-peptide index, ΔC30/ΔG30 (ng/mL per mmol/L)	0.412	0.318
TGs (mmol/L)	0.757	0.001
TCs (mmol/L)	0.589	0.023
HDL (mmol/L)	0.451	0.192
LDL (mmol/L)	0.489	0.122
GPT (U/L)	0.324	0.503
GOT (U/L)	0.222	0.753
hsCRP (mg/dl)	0.434	0.227
TNF (ng/L)	0.258	0.672
IL6 (pg/mL)	0.661	0.003

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; HOMA-IR: homeostasis model assessment of insulin resistance; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides.