Research Article
The Abnormal Expression of MicroRNA-542-3p in Hepatocellular Carcinoma and Its Clinical Significance
Table 3
Association of miRNA-542-3p expression with clinicopathological parameters in HCC.
| Clinical parameters | | miRNA-542-3p relative expression (2−ΔΔCt) | Mean ± SD | t | |
| Age | <50 | 24 | 0.829 ± 1.200 | 0.048 | 0.961 | ≥50 | 48 | 0.843 ± 1.213 | Gender | Male | 59 | 0.907 ± 1.218 | 1.026 | 0.308 | Female | 13 | 0.530 ± 1.101 | AFP (ng/mL) | <400 | 33 | 0.854 ± 1.264 | −0.102 | 0.919 | ≥400 | 39 | 0.825 ± 1.158 | Cirrhosis | Negative | 28 | 1.065 ± 1.289 | −1.248 | 0.218 | Positive | 44 | 0.694 ± 1.130 | Size (cm) | <10 | 29 | 1.362 ± 1.330 | −3.047 | 0.004 | ≥10 | 43 | 0.485 ± 0.967 | Differentiation | High | 21 | 1.497 ± 1.379 | −2.794 | 0.009 | Low/moderate | 51 | 0.567 ± 1.012 | TNM stage | I-II | 28 | 0.582 ± 1.056 | 1.459 | 0.149 | III-IV | 44 | 1.002 ± 1.267 | HBV | Negative | 25 | 0.623 ± 1.039 | 1.187 | 0.240 | Positive | 47 | 0.953 ± 1.272 | Portal invasion | Negative | 27 | 1.483 ± 1.351 | −3.514 | 0.001 | Positive | 45 | 0.452 ± 0.914 |
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Data are presented as mean ± SD. . . |