Research Article

Indoxyl Sulfate Elimination in Renal Replacement Therapy: Influence of Citrate- versus Acetate-Buffering Component during Bicarbonate Dialysis

Table 3

IS concentrations and calculated values in the study group.

Treatment modalityPredialysis IS concentration (μmol/l)Postdialysis IS concentration (μmol/l)Predialysis IS/TPROT ratio (μmol/g)Postdialysis IS/TPROT ratio (μmol/g)Difference in IS/TPROT ratio (μmol/g) values between RRT procedures

ACET-HD175 (126; 237)98.8 (52.8; 145)2.55 (1.82; 3.46)1.35 (0.67; 1.96)1.15 (0.61; 2.10)a versus b < 0.001c0.018d < 0.001
CIT-HD143 (103; 212)133 (101; 200)2.30 (1.64; 3.23)1.80 (1.32; 2.580.32 (0.07; 0.63)b versus c < 0.001d0.062 (n.s.)
ACET-HDF157 (100; 227)83.7 (56.2; 135)2.28 (1.37; 3.26)1.17 (0.78; 1.85)0.89 (0.53; 1.66)c versus d < 0.001
CIT-HDF135 (92.2; 179)107 (73.8; 157)2.10 (1.43; 2.70)1.39 (0.99; 2.15)0.44 (0.27; 0.77)

The statistical difference between predialysis values was not found. a = ACET-HD; b = CIT-HD; c = ACET-HDF; d = CIT-HDF procedure.