Research Article
Indoxyl Sulfate Elimination in Renal Replacement Therapy: Influence of Citrate- versus Acetate-Buffering Component during Bicarbonate Dialysis
Table 3
IS concentrations and calculated values in the study group.
| Treatment modality | Predialysis IS concentration (μmol/l) | Postdialysis IS concentration (μmol/l) | Predialysis IS/TPROT ratio (μmol/g) | Postdialysis IS/TPROT ratio (μmol/g) | Difference in IS/TPROT ratio (μmol/g) | values between RRT procedures |
| ACET-HD | 175 (126; 237) | 98.8 (52.8; 145) | 2.55 (1.82; 3.46) | 1.35 (0.67; 1.96) | 1.15 (0.61; 2.10) | a versus b < 0.001c0.018d < 0.001 | CIT-HD | 143 (103; 212) | 133 (101; 200) | 2.30 (1.64; 3.23) | 1.80 (1.32; 2.58 | 0.32 (0.07; 0.63) | b versus c < 0.001d0.062 (n.s.) | ACET-HDF | 157 (100; 227) | 83.7 (56.2; 135) | 2.28 (1.37; 3.26) | 1.17 (0.78; 1.85) | 0.89 (0.53; 1.66) | c versus d < 0.001 | CIT-HDF | 135 (92.2; 179) | 107 (73.8; 157) | 2.10 (1.43; 2.70) | 1.39 (0.99; 2.15) | 0.44 (0.27; 0.77) | |
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The statistical difference between predialysis values was not found. a = ACET-HD; b = CIT-HD; c = ACET-HDF; d = CIT-HDF procedure.
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