Application of Lactoferrin and α1-Antitrypsin in Gingival Retention Fluid to Diagnosis of Periodontal Disease

Table 1

Clinical data of the study subjects.

Variable	Levels
Age, years	48 ± 16
Gender (men/women), number	33/30
Prevalence of PD ≥ 4 mm (%)	10.5 (1.1–30.9)
Subjects with ≥30% of PD ≥ 4 mm, number (%)	16 (25%)
BOP (%)	19.8 (10.5–45.8)
Subjects with ≥20% of BOP, number (%)	31 (49%)
Lactoferrin in GRF (ng/mL)	61.0 (33.8–117.8)^a
Lactoferrin in saliva (ng/mL)	3611.9 (2789.1–7751.2)^a
α1-antitrypsin in GRF (ng/mL)	54.7 (23.2–212.5)^b
α1-antitrypsin in saliva (ng/mL)	4573.3 (2122.0–10834.1)^b

PD: probing pocket depth, BOP: bleeding on probing, GRF: gingival retention fluid. The data are presented as the mean ± standard deviation, median (interquartile range), or patient number (%). Significance level (gingival sulcus vs. saliva; ^alactoferrin, ^bα1-antitrypsin): .