Clinical Value of Combined Determination of Serum B7-H4 with Carcinoembryonic Antigen, Osteopontin, or Tissue Polypeptide-Specific Antigen for the Diagnosis of Colorectal Cancer

Figure 1

ROC curves of B7-H4/OPN/TPS/CEA of CRC patients. Receiver operating characteristic (ROC) curve analysis using four biomarkers to differentiate patients. Diagnostic accuracy of biomarkers was determined by obtaining the largest possible area under the curve (AUC) in ROC analysis. (a) B7-H4, (b) OPN, (c) TPS, (d) CEA, (e) B7-H4 + OPN, (f) B7-H4 + TPS, and (g) B7-H4 + CEA.

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