Research Article

CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression

Figure 1

CXCR4 and CXCL12 expression in luminal B BC samples. (a) Immunohistochemical analysis showing a higher expression of CXCR4 protein in the primary tumors of relapsing compared to relapse-free luminal B BC patients. (b) Immunohistochemical analysis of CXCL12 protein levels in the primary tumors of relapsing and relapse-free luminal B BC patients. (i) 10x magnification and (ii) 20x magnification.
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