CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression

<div>Immunohistochemical staining for CXCR4, vimentin, and CD163-positive macrophages in luminal B BC samples. (a) Immunohistochemical analysis of CXCR4 protein levels and the presence of CD163-positive macrophages in the primary tumors of relapsing and relapse-free luminal B BC patients. (b) Evaluation of Ki67 and vimentin protein expression in the primary tumors of relapsing and relapse-free luminal B BC patients. (i) 10x magnification and (ii) 20x magnification.</div>

Disease Markers

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Figure 2: CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression 

Figure 2 | CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression 