Research Article
Clinical Applications of Adiponectin Measurements in Type 2 Diabetes Mellitus: Screening, Diagnosis, and Marker of Diabetes Control
Table 1
Clinical and anthropometric characteristics of study subjects screened for glycemic status grouped by degree of adiposity.
| BMI (kg/m2) | Normal (BMI < 25) | Overweight (24.9–30) | Obese (>30) | (Kruskal-Wallis) |
| Age (yrs) | 25.7 ± 8.2 | 28.9 ± 8.9 | 31.8 ± 8.8 | <0.0001 | WC (cms) | 83.8 ± 9.2 | 95 ± 9 | 108.7 ± 12.6 | <0.0001 | SBP (mm/Hg) | 109 ± 10 | 115 ± 15 | 116 ± 13 | 0.001 | DBP (mm/Hg) | 69 ± 8 | 72 ± 8 | 74 ± 7 | <0.0001 | TC (mmol/L) | 4.48 ± 0.82 | 4.93 ± 0.98 | 5.15 ± 1.13 | <0.0001 | TG (mmol/L) | 0.81 ± 0.54 | 1.09 ± 0.72 | 1.32 ± 0.95 | <0.0001 | HDL-C (mmol/L) | 1.25 ± 0.36 | 1.18 ± 0.33 | 1.16 ± 0.31 | 0.23 | LDL-C (mmol/L) | 2.79 ± 0.71 | 3.04 ± 0.83 | 3.34 ± 0.92 | <0.0001 | ALT (IU/L) | 22.52 ± 17.05 | 24.63 ± 15.34 | 27.37 ± 16.57 | <0.0001 | Insulin (μU/mL) | 5.38 ± 4.68 | 6.8 ± 6.07 | 10.86 ± 9.47 | <0.0001 | S% | 143.19 ± 59.44 | 122.24 ± 54.92 | 94.4 ± 51.81 | <0.0001 | B% | 87.55 ± 36.83 | 100.43 ± 67.71 | 111.05 ± 54.5 | <0.0001 | HOMA-IR | 0.9 ± 0.65 | 1.07 ± 0.74 | 1.46 ± 1.04 | <0.0001 | Glucose (mmol/L) | 5 ± 0.99 | 5.05 ± 0.66 | 5.22 ± 1.03 | 0.03 | HbA1c (%) | 5.88 ± 0.83 | 5.87 ± 0.62 | 8.75 ± 26.39 | 0.001 | Adiponectin (μg/mL) | 8.95 ± 3.82 | 8.57 ± 5.12 | 6.82 ± 2.97 | <0.0001 |
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Abbreviations: WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; ALT: alanine aminotransferase; S%: insulin sensitivity; B%: beta cell function; HOMA-IR: homeostasis model assessment of insulin resistance; HbA1c: hemoglobin A1c. Data are presented as mean ± standard deviation
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