Clinical Applications of Adiponectin Measurements in Type 2 Diabetes Mellitus: Screening, Diagnosis, and Marker of Diabetes Control

Table 3

Clinical and anthropometric characteristics of type 2 diabetic subjects grouped by achievement of target HbA1c.

HbA1c	<53 mmol/mol	>53 mmol/mol	Mann–Whitney U
Age	55.4 ± 13.5	57.8 ± 9.4	NS
WC (cms)	102.6 ± 13.2	107 ± 12.9	NS
BMI (kg/m^2)	30.3 ± 7.7	32.8 ± 6.0	0.05
SBP (mm/Hg)	132 ± 28	132 ± 20	NS
DBP (mm/Hg)	82 ± 13	82 ± 12	NS
TC (mmol/L)	4.88 ± 1.11	5.02 ± 1.18	NS
TG (mmol/L)	1.54 ± 1.06	1.75 ± 1.19	NS
HDL-C (mmol/L)	1.21 ± 0.34	1.11 ± 0.29	0.04
LDL-C (mmol/L)	3.07 ± 0.95	3.04 ± 0.98	NS
ALT (IU/L)	21.91 ± 12.72	34.15 ± 177.75	0.02
Insulin (μU/mL)	11.51 ± 14.74	17.15 ± 25.48	NS
S%	88.05 ± 41.30	73.46 ± 50.21	0.03
B%	77.08 ± 53.19	43.40 ± 37.69	<0.0001
HOMA-IR	1.51 ± 1.04	2.31 ± 2.0	0.03
Glucose (mmol/L)	6.73 ± 2.03	11.23 ± 4.08	<0.0001
HbA1c (%)	6.34 ± 0.47	10.69 ± 2.53	<0.0001
Adiponectin (μg/mL)	8.58 ± 4.5	7.37 ± 4.35	0.04

Abbreviations: WC: waist circumference; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; ALT: alanine aminotransferase; S%: insulin sensitivity; B%: beta cell function; HOMA-IR: homeostasis model assessment of insulin resistance; HbA1c: hemoglobin A1c; NS: not significant (). Data are presented as mean ± standard deviation