Clinical Applications of Adiponectin Measurements in Type 2 Diabetes Mellitus: Screening, Diagnosis, and Marker of Diabetes Control
Table 4
Multivariate regression analysis of the associations of cardiometabolic variables with adiponectin concentration as a dependent variable in subjects screened for type 2 diabetes mellitus.
β coefficient
95% confidence interval
β coefficient
95% confidence interval
WC (cms)
−0.341
−0.114 to −0.066
<0.0001
−0.314
−0.178 to −0.008
0.023
BMI (kg/m2)
−0.224
−0.211 to −0.062
<0.0001
0.220
−.028 to 0.348
0.059
SBP (mm/Hg)
−0.151
−0.086 to −0.018
0.003
−0.045
−0.082 to 0.055
0.695
DBP (mm/Hg)
−0.160
−0.138 to −0.033
0.002
−.097
−0.178 to 0.074
0.415
TC (mmol/L)
−0.187
−1.325 to −0.421
<0.0001
−0.145
−2.701 to 1.343
0.507
TG (mmol/L)
−0.291
−2.269 to −1.159
< 0.0001
−0.135
−1.927 to 0.346
0.172
HDL-C (mmol/L)
0.338
3.170 to 5.578
<0.0001
0.309
1.397 to 6.588
0.003
LDL-C (mmol/L)
−0.240
−1.809 to −0.759
<0.0001
−0.161
−2.865 to 1.085
0.376
ApoA1 (g/L)
0.136
0.169 to 3.673
0.032
−.462
−13.608 to −2.371
0.006
Apo B (g/L)
−0.269
−4.647 to −1.995
< 0.0001
−0.271
−1.165 to −0.502
<0.0001
HOMA-IR
−0.252
−1.550 to −0.548
<0.0001
−0.166
−1.377 to −0.012
004
Glucose (mmol/L)
−0.173
−1.247 to −0.352
<0.0001
−0.097
−0.791 to 0.039
0.076
HbA1c (mmol/mol)
−0.061
−0.050 to 0.012
0.227
0.055
−0.672 to 1.286
0.054
Abbreviations: WC: waist circumference; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; Apo A1: apolipoprotein A1; Apo B: apolipoprotein B; HbA1c: hemoglobin A1c; SBP: systolic blood pressure; DBP: diastolic blood pressure; HOMA-IR: homeostasis model assessment of insulin resistance; β: inclusion of all cardiometabolic variables in the regression model.
