Clinical Significance of Hemostatic Parameters in the Prediction for Type 2 Diabetes Mellitus and Diabetic Nephropathy

Table 3

Logistic regression analysis of hemostatic assays in T2DM without complications.

Variables	Univariate regression			Multivariate regression
	OR	95% CI		OR	95% CI
PT	1.762	(1.168–2.659)	0.007	0.958	(0.915–2.128)	0.145
INR	3.521	(2.614–4.195)	0.000	0.950	(0.911–2.015)	0.105
APTT	1.555	(1.285–1.730)	0.000	1.320	(1.137–1.650)	0.002
FIB	1.338	(0.886–2.021)	0.167	0.872	(0.422–1.831)	0.712
PLT	1.388	(1.188–1.597)	0.000	1.211	(1.021–1.387)	0.003
D-D	1.002	(1.000-1.004)	0.019	0.999	(0.993–1.006)	0.887
FDR	1.006	(1.001–1.011)	0.002	0.996	(0.978–1.015)	0.708
TT	0.945	(0.768–1.260)	0.698	1.119	(0.764–1.638)	0.563

T2DM: type 2 diabetes mellitus; PT: prothrombin time; INR: international normalized ratio; aPTT: activated partial thromboplastin time; FIB: fibrinogen; PLT: platelet count; D-D: D-dimer; FDR: fibrinogen-D-dimer ratio; TT: thrombin time; OR: odds ratio; CI: confidence interval.