Clinical Significance of Hemostatic Parameters in the Prediction for Type 2 Diabetes Mellitus and Diabetic Nephropathy

Table 4

Regression analysis of hemostatic assays in T2DM patients with nephropathy.

Variables	Univariate regressions			Multivariate regression
	OR	95% CI		OR	95% CI
PT	1.080	(0.975–1.197)	0.139	0.982	(0.802–4.804)	0.236
INR	1.4981	(0.604–3.715)	0.383	1.101	(0.588–2.566)	0.412
APTT	1.037	(0.970–1.110)	0.925	0.981	(0.848–3.778)	0.931
FIB	1.972	(1.437–2.669)	0.000	1.611	(1.338–2.122)	0.001
PLT	1.305	(1.101–1.509)	0.000	1.194	(1.039–1.411)	0.009
D-D	1.122	(1.008–1.212)	0.000	1.055	(0.939–1.124)	0.312
FDR	1.001	(1.000–1.002)	0.007	0.995	(0.974–1.036)	0.479
TT	0.933	(0.704–1.237)	0.631	0.958	(0.681–1.377)	0.805

T2DM: type 2 diabetes mellitus; PT: prothrombin time; INR: international normalized ratio; aPTT: activated partial thromboplastin time; FIB: fibrinogen; PLT: platelet count; D-D: D-dimer; FDR: fibrinogen-D-dimer ratio; TT: thrombin time; OR: odds ratio; CI: confidence interval.