The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer

Figure 4

The expression of p21 (a), Noxa (b), and CES2 (c) was quantified by real-time reverse transcriptase PCR. Human colorectal cancer cell lines with TP53 missense mutations (SW480 and KM12C) were treated with 120 μM PRIMA-1^MET for 24 hours. GAPDH was used as a reference gene. Data represent the mean values ± SEM (). ; n.s.: no significance. A paired two-tailed t-test was used.

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