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Disease Markers
Volume 2018 (2018), Article ID 5604702, 5 pages
https://doi.org/10.1155/2018/5604702
Research Article

The Role of Serum CK18, TIMP1, and MMP-9 Levels in Predicting R0 Resection in Patients with Gastric Cancer

1Department of General Surgery, Haseki Training and Research Hospital, Istanbul, Turkey
2Department of General Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey
3Department of General Surgery, Kemerburgaz University School of Medicine, Istanbul, Turkey

Correspondence should be addressed to Cihad Tatar

Received 12 September 2017; Revised 9 November 2017; Accepted 4 December 2017; Published 5 February 2018

Academic Editor: Paola Gazzaniga

Copyright © 2018 Sevki Peduk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Zhang, J. Wang, W. Liu et al., “Cytokeratin 18 knockdown decreases cell migration and increases chemosensitivity in non-small cell lung cancer,” Journal of Cancer Research and Clinical Oncology, vol. 142, no. 12, pp. 2479–2487, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. H. Nagase and J. F. Woessner Jr., “Matrix metalloproteinases,” The Journal of Biological Chemistry, vol. 274, no. 31, pp. 21491–21494, 1999. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Westermarck and V. M. Kahari, “Regulation of matrix metalloproteinase expression in tumor invasion,” The FASEB Journal, vol. 13, no. 8, pp. 781–792, 1999. View at Google Scholar
  4. G. I. Goldberg, A. Strongin, I. E. Collier, L. T. Genrich, and B. L. Marmer, “Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin,” The Journal of Biological Chemistry, vol. 267, no. 7, pp. 4583–4591, 1992. View at Google Scholar
  5. M. W. Olson, D. C. Gervasi, S. Mobashery, and R. Fridman, “Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2,” The Journal of Biological Chemistry, vol. 272, no. 47, pp. 29975–29983, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Watanabe, Y. Takahashi, T. Ohta, M. Mai, T. Sasaki, and M. Seiki, “Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice,” Cancer, vol. 77, no. 8, pp. 1676–1680, 1996. View at Publisher · View at Google Scholar
  7. S. Aznavoorian, A. N. Murphy, W. G. Stetler-Stevenson, and L. A. Liotta, “Molecular aspects of tumor cell invasion and metastasis,” Cancer, vol. 71, no. 4, pp. 1368–1383, 1993. View at Publisher · View at Google Scholar
  8. L. A. Torre, F. Bray, R. L. Siegel, J. Ferlay, J. Lortet-Tieulent, and A. Jemal, “Global cancer statistics, 2012,” CA: A Cancer Journal for Clinicians, vol. 65, no. 2, pp. 87–108, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Makino, M. Yamasaki, A. Takeno et al., “Cytokeratins 18 and 8 are poor prognostic markers in patients with squamous cell carcinoma of the oesophagus,” British Journal of Cancer, vol. 101, no. 8, pp. 1298–1306, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. Y. Messai, M. Z. Noman, A. Derouiche et al., “Cytokeratin 18 expression pattern correlates with renal cell carcinoma progression: relationship with Snail,” International Journal of Oncology, vol. 36, no. 5, pp. 1145–1154, 2010. View at Publisher · View at Google Scholar
  11. T. Fillies, R. Werkmeister, J. Packeisen et al., “Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity,” BMC Cancer, vol. 6, no. 1, pp. 10–15, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Knosel, V. Emde, K. Schluns, P. M. Schlag, M. Dietel, and I. Petersen, “Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays,” Cellular Oncology, vol. 28, no. 4, pp. 167–175, 2006. View at Google Scholar
  13. H. Buhler and G. Schaller, “Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo,” Molecular Cancer Research, vol. 3, no. 7, pp. 365–371, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. L. C. Scott, T. R. J. Evans, J. Cassidy et al., “Cytokeratin 18 in plasma of patients with gastrointestinal adenocarcinoma as a biomarker of tumour response,” British Journal of Cancer, vol. 101, no. 3, pp. 410–441, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Oyama, S. Fushida, J. Kinoshita et al., “Serum cytokeratin 18 as a biomarker for gastric cancer,” Clinical and Experimental Medicine, vol. 13, no. 4, pp. 289–295, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Bilici, “Cytokeratin 18 for chemotherapy efficacy in gastric cancer,” Translational Gastrointestinal Cancer, vol. 4, pp. 200–206, 2015. View at Google Scholar
  17. S. Zhang, L. Li, J. Y. Lin, and H. Lin, “Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma,” World Journal of Gastroenterology, vol. 15, pp. 899–904, 2003. View at Publisher · View at Google Scholar
  18. Y. Q. Shan, R. C. Ying, C. H. Zhou et al., “MMP-9 is increased in the pathogenesis of gastric cancer by the mediation of HER2,” Cancer Gene Therapy, vol. 22, no. 3, pp. 101–107, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Zhang, G. Y. Zhu, H. Y. Gao, S. P. Zhao, and Y. Xue, “Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma,” Journal of Surgical Oncology, vol. 103, no. 3, pp. 243–247, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. V. Muntean, “Staging laparoscopy in gastric cancer. Accuracy and impact on therapy,” Journal of Gastrointestinal and Liver Diseases, vol. 18, no. 2, pp. 189–195, 2009. View at Google Scholar
  21. G. Buccheri and D. Ferrigno, “Serum biomarkers facilitate the recognition of early-stage cancer and may guide the selection of surgical candidates: a study of carcinoembryonic antigen and tissue polypeptide antigen in patients with operable non–small cell lung cancer,” The Journal of Thoracic and Cardiovascular Surgery, vol. 122, no. 5, pp. 891–899, 2001. View at Publisher · View at Google Scholar · View at Scopus