Plasma Heme Oxygenase-1 Levels in Patients with Coronary and Peripheral Artery Diseases

Table 4

Factors associated with CAD or PAD (multiple logistic regression analysis of the 410 study patients).

	Odds ratio	(95% CI)	value
CAD
Age (per 10 yrs increase)	1.52	(1.24–1.85)	<0.001
Male gender	1.79	(1.11–2.88)	<0.02
Statin use	2.01	(1.27–3.17)	<0.005
Diabetes	2.92	(1.72–4.93)	<0.001
HO-1 level (<0.35 ng/mL)	0.65	(0.42–0.99)	<0.05
PAD
Age (per 10 yrs increase)	1.79	(1.20–2.68)	<0.005
Statin use	2.41	(1.17–4.94)	<0.02
Smoking	2.50	(1.21–5.13)	<0.02
HO-1 level (<0.35 ng/mL)	2.12	(1.03–4.37)	<0.02

The dependent variables were the presence of CAD or PAD. The analysis included age, gender, hypertension, hyperlipidemia, statin use, diabetes, smoking, and HO-1 level (<0.35 ng/mL).