Usefulness of EEG Techniques in Distinguishing Frontotemporal Dementia from Alzheimer’s Disease and Other Dementias

Figure 3

Boxplots of selected features: AD versus DLBPD: 23 of 25 features resulted in significant differences. The features with the lowest values () were the GC at P7/P8 and P8/P7 (a). Center frequency and relative band power α and β1 were higher in AD patients than in DLBPD patients at all sites with significantly different results. The opposite was true for automutual information, band ratios, relative band power , and cross-mutual information. AD versus bvFTD: 17 features resulted in significant differences with GC and phase coherence β1 reaching the lowest value of at T7/T8. GC was significantly higher in bvFTD patients than in AD patients while phase coherence was significantly higher in AD patients (b). Phase coherences α and β1 were significantly higher in AD patients than in bvFTD patients at all sites with significantly different results. The opposite was observed for coherence β1 and GC. bvFTD versus DLBPD: 12 features resulted in significant differences with relative band power β1 at P8 and ratio 4 at P8 having the lowest value of and , respectively. Automutual information and mutual information were higher in DLBPD patients than in bvFTD patients at all sites with significantly different results. The opposite was then evident for center frequency. Legend: DLBPD = PDD or probable DLB; bvFTD = behavioral variant of FTD; AD = Alzheimer’s disease; GC = Granger causality. Reproduced with permission from Garn et al. [28] in 2017.

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