Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer

<div>Downregulation of miR-29c abolishes the TUG1 knockdown-mediated inhibition of the proliferative and invasive abilities of BxPC-3 and PANC-1 cells. (a) CCK-8 was used to measure the proliferation of PANC-1 cells after the indicated treatment. (b) Transwell assay was used to measure the invasive ability of PANC-1 cells after the indicated treatment. (c) Wound healing assay was used to measure the migratory ability of PANC-1 cells after the indicated treatment. (d) Expressions of ITGB1, MMP2, MMP9, and EMT marker factors (E-cadherin, N-cadherin, and Vimentin) were measured by Western blot after the indicated treatment (left) and then quantified (right). 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Disease Markers

fig4

Figure 4

Figure 4: Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer 