Grading of Neuroendocrine Carcinomas: Correlation of ⁶⁸Ga-PET/CT Scan with Tissue Biomarkers

Table 5

Correlation between ATRX + DAXX and RB1 expression and best response to first-line chemotherapy.

	Best response
	Overall		value	Pancreatic		GI
	PD (%)	SD + PR (%)		PD (%)	SD + PR (%)	PD (%)	SD + PR (%)
Overall	3 (33.3)	6 (66.7)		1 (33.3)	2 (66.7)	2 (33.3)	4 (66.7)
ATRX + DAXX
Negative	0 (0.0)	3 (50.0)	0.464	0 (0.0)	0 (0.0)	0 (0.0)	3 (75.0)
Positive	3 (100.0)	3 (50.0)		1 (100.0)	2 (100.0)	2 (100.0)	1 (25.0)
RB1
Negative	1 (33.3)	4 (66.7)	0.524	0 (0.0)	1 (50.0)	1 (50.0)	3 (75.0)
Positive	2 (66.7)	2 (33.3)		1 (100.0)	1 (50.0)	1 (50.0)	1 (25.0)

PD: progressive disease; SD: stable disease; PR: partial response; GI: gastrointestinal. -value was calculated on the overall number of patients.