Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics

Table 2

Characteristics of the patients with complicated febrile neutropenia.

Gender/age (years)	Blood culture	Time	Characteristics of severe sepsis	qSOFA	ICU	Outcome
M/65	Pseudomonas aeruginosa	1	Pneumonia, respiratory failure	3	Yes	Died
F/70	Negative, RSV-pneumonia	6	Pneumonia, septic shock	2	Yes	Died
M/47	Enterococcus faecium	4	Pneumonia, respiratory failure	1	Yes	Died
M/67	Negative	7	Pneumonia, respiratory failure	2	Yes	Recovered
M/58	Staphylococcus epidermidis	2	Septic shock, respiratory failure	2	Yes	Recovered
M/63	Enterococcus faecium	5	Respiratory failure, ileus	2	Yes	Recovered
M/68	Streptococcus mitis	11	Respiratory failure (need for NIV)	2	No (CCU)	Recovered
M/51	Enterococcus faecium	1	Low blood pressure, need for plasma expander	1	No	Recovered
F/65	Streptococcus mitis	—	—	—	No	Recovered
M/41	Streptococcus salivarius	—	—	—
M/31	Gemella morbillorum	—	—	—	No	Recovered
M/62	Staphylococcus haemolyticus	—	—	—	No	Recovered
M/36	Staphylococcus haemolyticus	—	—	—	No	Recovered
F/62	Staphylococcus epidermidis	—	—	—	No	Recovered
M/65	Staphylococcus epidermidis	—	—	—	No	Recovered
M/69	Enterococcus faecium	—	—	—	No	Recovered
M/58	Enterococcus faecium	—	—	—	No	Recovered
F/49	Klebsiella oxytoca	—	—	—	No	Recovered
F/56	Escherichia coli	—	—	—	No	Recovered
M/61	Candida krusei	—	—	—	No	Recovered

M: male; F: female; Time: days from the onset of fever to severe sepsis; qSOFA: quick sepsis-related organ failure assessment; ICU: intensive care unit; NIV: noninvasive ventilation; CCU: cardiac care unit.