Disease Markers

Research Article

A Comparison of Ki67, Syndecan-1 (CD138), and Molecular RANK, RANKL, and OPG Triad Expression in Odontogenic Keratocyts, Unicystic Ameloblastoma, and Dentigerous Cysts

Table 1

Positive cell mean for RANK, RANKL, and OPG in odontogenic keratocyst, dentigerous cyst, and unicystic ameloblastoma.


Type of lesion (number of cases)	RANK		RANKL		OPG
Type of lesion (number of cases)	Mean		Mean		Mean

Lining epithelium
OKC (22)	180.95	0.3879^a	43.59	0.4153^g	117.90	0.0121^m
DC (17)	249.47	0.7693^b	26.52	0.0317^h	11.47	0.0211ⁿ
UA (19)	212.47	0.8053^c	62.47	0.3205ⁱ	6.89	0.9928^o
Stroma
OKC (22)	101.38	0.0036^d	34.27	0.0004^j	54.09	0.0018^p
DC (17)	169.94	0.3072^e	27.11	0.5292^k	14.35	0.0196^q
UA (19)	139.00	0.1414^f	60.73	0.0001^l	4.00	0.7629^r

= 1.8886 (RANK epithelium), = 7.7653 (RANK stroma), = 13.3295 (RANKL epithelium), = 15.9150 (RANKL stroma), = 4.2004 (OPG epithelium), = 12.24 (OPG stroma). OKC: odontogenic keratocyst; DC: dentigerous cyst; and UA: unicystic ameloblastoma. Mean differences test by pair of lesions (Tukey): ^aOKC versus DC, ^bDC versus UA, ^cUA versus OKC, ^dOKC versus DC, ^eDC versus UA, ^fUA versus OKC, ^gOKC versus DC, ^hDC versus UA, ⁱUA versus OKC, ^jOKC versus UA, ^kDC versus OKC, ^lUA versus DC, ^mOKC versus UA, ⁿDC versus OKC, ^oUA versus DC, ^pOKC versus UA, ^qDC versus OKC, ^rUA versus DC.