Evaluation of Individual and Combined Markers of Urine Dipstick Parameters and Total Lymphocyte Count as a Substitute for CD4 Count in Low-Resource Communities in Ghana

Table 5

Combined diagnostic performance of urine dipstick biochemistry and TLC as alternative markers for CD4.

Markers	Sensitivity	Specificity	PPV	NPV	AUC ( value)
≤1200 TLC + leukocyturia ≥ 2++	76.2%	100.0%	100.0%	87.3%	0.937 ()
≤1200 TLC + proteinuria ≥ 2++	88.1%	100.0%	100.0%	93.8%	0.978 ()
≤1200 TLC + hematuria ≥ 2++	83.3%	100.0%	100.0%	89.2%	0.960 ()
≤1200 TLC + ≥2++ (Leu + Pro + Hem)	72.8%	100.0%	100.0%	97.9%	0.980 ()

Leu: leukocyturia; Pro: proteinuria; Hem: hematuria.