Clinical and Biological Predictors of Plasma Levels of Soluble RAGE in Critically Ill Patients: Secondary Analysis of a Prospective Multicenter Observational Study

Figure 5

Multidimensional analyses. (a) Principal component analysis (PCA) of clinical and biological variables (significant in univariate analysis) against log-transformed plasma sRAGE. The first two axes of PCA were chosen, as they represent 31% of total inertia and because including other axes did not influence the results (data not shown). PCA suggests an absence of correlation between plasma sRAGE and selected variables. (b) Multiple correspondence analysis (MCA) with mixed quantitative and qualitative variables against plasma sRAGE as subdivided into quartiles. No significant association between quartiles of sRAGE and selected variables was found. [1], [2], [3], and [4] represent the 1st, 2nd, 3rd, and 4th quartiles, respectively. sRAGE: soluble form of the receptor for advanced glycation end products.

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