Clinical and Biological Predictors of Plasma Levels of Soluble RAGE in Critically Ill Patients: Secondary Analysis of a Prospective Multicenter Observational Study

Figure 6

Multidimensional analyses. (a) Principal component analysis (PCA) of clinical and biological variables (significant in univariate analysis) against log-transformed plasma esRAGE. The first two axes of PCA were chosen as they represent 26% of total inertia, and because including other axes did not influence the results (data not shown). PCA suggests an absence of correlation between plasma esRAGE and selected variables. (b) Multiple correspondence analysis (MCA) with mixed quantitative and qualitative variables against plasma esRAGE as subdivided into quartiles. No significant association between quartiles of esRAGE and selected variables was found. [1], [2], [3], and [4] represent the 1st, 2nd, 3rd, and 4th quartiles, respectively. esRAGE: endogenous secretory form of the receptor for advanced glycation end products.

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