Lack of Association between Interleukin-1β Gene Polymorphism (rs16944) and Chronic Periodontitis: From a Case-Control Studies to an Updated Meta-Analysis

Table 3

Overall analysis of the association between IL-1β polymorphism (rs16944) and susceptibility to chronic periodontitis.

Models	Group	Heterogeneity		Model	OR	95% CI		Egger’s
		C vs. T	All						<0.001	63.39	Random	0.93	0.774–1.128	0.48	0.45
Asian	0.001		68.53	Random	0.84	0.655–1.083	0.18	0.85
Caucasian	0.028		57.71	Random	1.08	0.835–1.388	0.57	0.27
CC vs. CT + TT	All	0.008	51.83	Random	0.97	0.762–1.246	0.84	0.62
	Asian	0.066	45.47	Fixed	0.93	0.750–1.158	0.52	0.42
	Caucasian	0.016	61.52	Random	1.11	0.738–1.665	0.62	0.83
CC + CT vs. TT	All	<0.001	67.01	Random	0.90	0.658–1.232	0.51	0.76
	Asian	0.001	70.45	Random	0.76	0.503–1.149	0.19	0.77
	Caucasian	0.313	15.32	Fixed	1.34	1.017–1.758	0.037	0.83

OR: odds ratio; CI: confidence interval. Bold numbers indicate a significant value.