Prognostic Role of MicroRNAs in Human Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis

Table 1

Quality Assessment of the selected studies for systemic review and meta-analysis.

Criteria	Unsatisfactory	Satisfactory	Good
Sample size	Less than ten samples	10–100 samples	>100 samples
Cox regression analysis	Only value is given	Only multivariate analysis with HR, CI, and value	Both univariate and multivariate analysis
Survival	Only DFS	OS, DFS	OS, DFS, RFS
miRNAs regulation	No significant upregulation or downregulation	At least one miRNA upregulated or downregulated	>1 miRNA upregulated or downregulated
Total studies	0	12	15

DFS: disease-free survival; OS: overall survival; RFS: recurrence-free survival; HR: hazard ratio; CI: confidence interval; miRNA: microRNA.