Serum Cytokine Profiles in Patients with Dengue Fever at the Acute Infection Phase
Table 2
Clinical routine indexes in infections and controls.
Primary infections (mean ± SD)
P value
Secondary infections (mean ± SD)
P value
Controls (E) (mean ± SD)
P value
1st week (A)
2nd week (B)
A versus E
B versus E
1st week (C)
2nd week (D)
C versus E
D versus E
A versus C
B versus D
Number of case
151
82
—
—
44
19
—
—
20
—
—
WBC (×109/L)
4.02 ± 2.57
3.79 ± 2.58
<0.001
<0.001
3.80 ± 1.83
4.00 ± 1.65
<0.001
<0.001
7.30 ± 1.51
0.840
0.242
PLT (×109/L)
104.07 ± 61.90
100.46 ± 59.68
<0.001
<0.001
105.23 ± 65.66
112.79 ± 74.43
<0.001
<0.001
248.70 ± 63.40
0.983
0.599
HCT
0.39 ± 0.05
0.39 ± 0.04
<0.001
<0.001
0.40 ± 0.04
0.39 ± 0.05
<0.001
<0.001
0.44 ± 0.04
0.366
0.562
ALT (U/L)
62.54 ± 79.63
62.72 ± 63.17
<0.001
<0.001
54.57 ± 71.40
74.22 ± 73.40
<0.001
<0.001
19.70 ± 8.25
0.679
0.316
AST (U/L)
76.60 ± 64.87
76.48 ± 63.68
<0.001
<0.001
77.16 ± 57.99
109.78 ± 148.19
<0.001
<0.001
18.50 ± 3.59
0.799
0.618
LDH (U/L)
297.16 ± 154.33
309.37 ± 111.52
<0.001
<0.001
322.97 ± 170.13
535.00 ± 502.20
<0.001
<0.001
151.40 ± 15.41
0.303
0.467
CK (U/L)
235.27 ± 262.68
273.98 ± 378.99
<0.001
<0.001
370.50 ± 500.50
3651.00 ± 10569.53
<0.001
0.009
74.55 ± 18.19
0.233
0.867
Cr (μmol/L)
84.38 ± 50.42
86.96 ± 60.76
0.056
0.068
82.68 ± 26.19
78.53 ± 11.85
0.072
0.094
71.45 ± 12.95
0.897
0.868
UREA (mmol/L)
3.71 ± 2.20
3.84 ± 1.92
0.001
0.003
3.48 ± 1.83
3.25 ± 1.38
0.001
0.002
4.64 ± 1.18
0.318
0.178
Mean ± SD of clinical routine indexes were presented and performed analysis using Mann–Whitney U test or t-test between two cohorts. The statistical significance is indicated by asterisks: .