Metabolomics of Hydrazine-Induced Hepatotoxicity in Rats for Discovering Potential Biomarkers

Table 1

Alterations of blood biochemistry parameters in hydrazine-treated rats.

Time	Dose	ALT (U/L)	ALP (U/L)	AST (U/L)
24 h	0 mg/kg	48.4 ± 14.8	199.5 ± 21.4	150.7 ± 34.9
	150 mg/kg	39.8 ± 10.2	180.1 ± 24.1	109.8 ± 55.5
48 h	0 mg/kg	47.3 ± 19.4	193.1 ± 41.0	131.2 ± 18.0
	150 mg/kg	31.3 ± 15.5^†	201.1 ± 27.5	86.6 ± 45.6^††

ALT: alanine aminotransferase; ALP: alkaline phosphatase; AST: aspartate aminotransferase. Significantly different from the 0 mg/kg group (24 h) (). †Significantly different from the 0 mg/kg group (48 h) (). ††Significantly different from the 0 mg/kg group (48 h) ().