Research Article

Microtubule-Associated Protein 4 Is a Prognostic Factor and Promotes Tumor Progression in Lung Adenocarcinoma

Table 2

Univariate and multivariate Cox regression analysis for OS in lung adenocarcinoma patients.

VariatesCategoriesUnivariate analysisMultivariate analysis
HR (95%CI) valueHR (95%CI) value

GenderMale versus female1.361 (0.843–2.199)0.207
Age>60 versus ≤60 years1.058 (0.654–1.711)0.818
DifferentiationPoor versus well/moderate1.025 (0.602–1.746)0.927
pTT3-4 versus T1-21.393 (0.771–2.516)0.272
pNN1-3 versus N02.767 (1.697–4.512)<0.0012.770 (1.642–4.674)<0.001
TNM stageII-III versus I2.474 (1.517–4.036)<0.001
MAP4 expressionHigh versus low1.714 (1.060–2.771)0.0281.655 (1.017–2.692)0.042

OS: overall survival; HR: hazard ratio; CI: confidence interval; p: pathological staging; TNM: tumor-node-metastasis; MAP4: microtubule-associated protein 4.