The Association between Glomerular Filtration Rate Estimated Using Different Equations and Mortality in the Japanese Community-Based Population: The Yamagata (Takahata) Study

Table 2

Hazard ratios for mortality by the baseline eGFR.

	eGFRcreat		eGFR-EPI		eGFRcys
eGFR category
Unadjusted	HR (95%CI)	value	HR (95%CI)	value	HR (95%CI)	value
eGFR ≥ 90	Reference		Reference		Reference
75–89	1.21 (0.76–1.93)	0.416	2.17 (1.03–5.58)	0.042	1.38 (0.75–2.68)	0.307
60–74	2.17 (1.45–3.34)	<0.001	5.39 (2.54–13.9)	<0.001	2.59 (1.49–4.84)	<0.001
<60	2.47 (1.34–4.38)	0.005	4.64 (19.3–12.8)	<0.001	6.63 (3.82–12.4)	<0.001
Age, gender-adjusted	HR (95%CI)	value	HR (95%CI)	value	HR (95%CI)	value
eGFR ≥ 90	Reference		Reference		Reference
75–89	1.04 (0.66–1.66)	0.808	0.82 (0.37–2.98)	0.67	0.94 (0.50–1.83)	0.840
60–74	1.37 (0.90–2.12)	0.143	1.07 (0.44–3.04)	0.883	1.28 (0.70–2.49)	0.432
<60	1.23 (0.66–2.22)	0.511	0.99 (0.37–2.98)	0.982	2.52 (1.33–5.08)	0.004
eGFR values
Per-15 mL/min/1.73 m^2 decrease	HR (95%CI)	value	HR (95%CI)	value	HR (95%CI)	value
Unadjusted	1.35 (1.17–1.56)	<0.001	1.55 (1.34–1.78)	<0.001	1.79 (1.55–2.07)	<0.001
Age, gender-adjusted	1.10 (0.95–1.28)	0.216	1.15 (0.94–1.38)	0.177	1.40 (1.18–1.67)	<0.001

eGFR: estimated glomerular filtration rate; HR: hazard ratio; CI: confidence interval.