Research Article
Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer
Table 3
Expression of pentose phosphate pathway-related metabolism-related proteins according to breast cancer subtype.
| Parameter | Total () (%) | Luminal A () (%) | Luminal B () (%) | HER-2 () (%) | TNBC () (%) | value |
| G6PDH | | | | | | <0.001 | Negative | 297 (85.3) | 149 (92.0) | 70 (83.3) | 14 (51.9) | 64 (85.3) | | Positive | 51 (14.7) | 13 (8.0) | 14 (16.7) | 13 (48.1) | 11 (14.7) | | 6PGL | | | | | | 0.009 | Negative | 261 (75.0) | 133 (82.1) | 58 (69.0) | 15 (55.6) | 55 (73.3) | | Positive | 87 (25.0) | 29 (17.9) | 26 (31.0) | 12 (44.4) | 20 (26.7) | | 6PGDH | | | | | | <0.001 | Negative | 343 (98.6) | 162 (100.0) | 84 (100.0) | 27 (100.0) | 70 (93.3) | | Positive | 5 (1.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 5 (6.7) | | NRF2 | | | | | | 0.894 | Negative | 311 (89.4) | 145 (89.5) | 76 (90.5) | 23 (85.2) | 67 (89.3) | | Positive | 37 (10.6) | 17 (10.5) | 8 (9.5) | 4 (14.8) | 8 (10.7) | |
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