Plasma Translocator Protein Levels and Outcomes of Acute Ischemic Stroke: A Pilot Study
Table 1
Baseline characteristics of 38 patients stratified into lower- and higher-translocator protein (TSPO) groups.
Total
Lower TSPO
Higher TSPO
(≤0.46 ng/ml)
(>0.46 ng/ml)
38
19
19
Female (%)
19
8 (42.1)
11 (57.9)
0.33
Age (years)
69.6 (14.9)
68.5 (13.4)
70.6 (16.5)
0.66
Glasgow Coma Scale
12.0 (3.8)
12.2 (3.7)
11.7 (4.1)
0.74
NIHSS score at the baseline
16.7 (7.9)
16.4 (8.7)
17.1 (7.4)
0.81
Hypertension (%)
27 (71.0)
12 (36.1)
15 (78.9)
0.28
Diabetes mellitus (%)
12 (31.5)
5 (26.3)
7 (36.8)
0.48
CAD (%)
9 (23.7)
3 (15.79)
6 (31.6)
0.25
CKD (%)
7 (18.4)
2 (10.5)
5 (26.3)
0.20
Smoker (%)
9 (23.7)
6 (31.58)
3 (15.8)
0.25
Hemoglobin (g/dl)
13.9 (2.7)
13.7 (3.2)
14.0 (2.1)
0.68
Platelets (103/μl)
215 (70)
209 (90)
221 (43)
0.61
WBCs (103/mm3)
11.0 (4.8)
11.6 (5.5)
10.3 (4.0)
0.45
BUN (mg/dl)
22.1 (12.7)
21.1 (11.3)
23.3 (14.7)
0.68
Creatinine (mg/dl)
1.50 (1.8)
1.54 (2.19)
1.46 (1.16)
0.89
CRP (mg/dl)
5.07 (7.2)
3.23 (5.16)
6.91 (5.65)
0.28
TOAST classification
Large artery atherothrombosis
24 (63.1)
12 (63.1)
12 (63.1)
1.0
Cardioembolism
12 (31.6)
6 (31.6)
6 (31.6)
Other determined causes
2 (5.3)
1 (5.3)
1 (5.3)
IV-t-PA (, %)
13(31.6)
8(42.1)
5(26.3)
0.49
Values are the mean (SD) or n (%), as appropriate. NIHSS, National Institutes of Health Stroke Scale; CAD, coronary artery disease; CKD, chronic kidney disease; WBCs, white blood count; CRP, highly sensitive C-reactive protein; TOAST, Trial of ORG 10172 in Acute Stroke Treatment; IV-t-PA, intravenous tissue plasminogen activator.
